|FUNCTION : Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY : 2 H 2O2= O 2+ 2 H 2O.
COFACTOR : HEME GROUP AND NADP.
SUBUNIT : Homotetramer.
SUBCELLULAR LOCATION : Peroxisomal.
DISEASE : Deficiency in CAT causes acatalasia (or acatalasemia). This disease is characteized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.
SIMILARITY : BELONGS TO THE CATALASE FAMILY.
Last Update 13-Mar-03