|FUNCTION : Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
SUBUNIT : ASSOCIATES WITH BETA-CATENIN.
TISSUE SPECIFICITY : Ubiquitous.
PTM : Phosphorylation on Ser-38 inhibits the actin-binding ability of fascin.
SIMILARITY : BELONGS TO THE FASCIN FAMILY.
Last Update 13-Mar-03