CATALYTIC ACTIVITY: (S)-lactate + NAD+ = pyruvate + NADH. * PATHWAY: Anaerobic glycolysis; final step. * SUBUNIT: Homotetramer. * SUBCELLULAR LOCATION: Cytoplasmic. * DISEASE: Defects in LDHA are a cause of exertional myoglobinuria. * SIMILARITY: BELONGS TO THE LDH FAMILY. |
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25-JAN-03
Last Update 13-Mar-03