FUNCTION: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. * SUBUNIT: HETERODIMER OF PSME1 AND PSME2, WHICH FORMS A HEXADIMERIC RING. PSME1 CAN FORM HOMOHEPTAMERS. * INDUCTION: BY INTERFERON GAMMA. * SIMILARITY: BELONGS TO THE PA28 FAMILY. |
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06-JAN-01
Last Update 13-Mar-03